TB-500

Also known as: Thymosin Beta-4, Tβ4

Clinical Trials
Healing

A naturally occurring peptide present in most human tissues. Plays a crucial role in tissue repair, cell migration, and wound healing.

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Mechanism of Action

TB-500 promotes cell migration by binding to and sequestering actin, a protein essential for cell movement. It upregulates actin expression, promotes angiogenesis, reduces inflammation, and facilitates hair follicle stem cell migration for wound healing.

Research Summary

Research shows significant wound healing acceleration, cardiac tissue repair after heart attack in animal models, and anti-inflammatory effects. Studies demonstrate improved recovery from dermal wounds and muscle injuries. Human clinical trials ongoing for wound healing applications.

Clinical Status:Clinical trials - Phase II trials for wound healing
Trial Progress:Phase II
Pre
I
II
III
IV
FDA

Research Protocols

Note: Doses observed in research studies

Common Doses

  • 2-2.5 mg twice weekly
  • 750 mcg in some protocols

Duration

4-6 weeks loading, then maintenance

Administration

Subcutaneous or intramuscular injection

Side Effects & Considerations

  • Headache
  • Temporary lethargy
  • Possible flu-like symptoms initially
  • Concerns about tumor growth in those with existing cancer (theoretical)

References

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Educational Information Only

This information is provided for educational purposes only and is not intended as medical advice. Always consult with qualified healthcare providers before making any decisions about peptides or other substances. The protocols listed reflect doses observed in research studies, not recommendations.